A little bit on the sugar splitting. :P

Glycolysis all began when there was this 6carbon sugar who wanted to be broken down into two molecules of 3C pyruvate. In other words he wanted to be split in half.

Image

Now for him to achieve his goal, he needed to undergo ten reactions! which were all being  catalyzed by ten different enzymes! What a long treacherous journey it was but he was successful. Now in the process of glycolysis there are four main events, that need special recognition.

1. In the beginning the hexose sugar (6C) have phosphates and energy added to them. In other words they are phosphorylated. This reaction uses up ATP.

2. The new phosphorylated sugar is then broken down into the two molecules of phosphorylated triose which means 3carbons. They are made into triose phosphate

3. At this point these triose phosphates will now lose their phosphate to ADP, regenerating a molecule of ATP,

4. The triose phosphates are also oxidised, which means they would lose a hydrogen to the coenzyme NAD, this now becomes reduced.

NAD+ + 2H+ + 2e- —–> NADH + H+

The over all reaction can be seen below

TCA-06

Its the reducing power of the NAD that can under aerobic conditions be used again in the mitochondria to generate more ATP in the electron transport chain as we will see later on. At the end of glycolysis there is pyruvate , ATP and well the reduced NAD.

For more detailed information glycolsis you can check out my review on glycolysis. 🙂

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